Table 3. Stratified analyses of rs35399661, rs3763338 and rs2844695 by the clinicopathology characteristics in ESCC.

	rs35399661			rs3763338			rs2844695
Clinicopathology characteristics (n)	F-Ab	?2	P	F-Ac	?2	P	F-Ad	?2	P
Tumor location#
upper thoracic (67)	0.17	3.592	0.166	0.14	3.166	0.205	0.42	0.274	0.254
middle thoracic (228)	0.11			0.09			0.39
lower thoracic (53)	0.14			0.08			0.32
Gross type*
MT (149)	0.11	1.018	0.759	0.07	4.812	0.17	0.39	0.198	0.978
UT (121)	0.14			0.12			0.38
ST (10)	0.10			0.15			0.35
FT (31)	0.13			0.06			0.39
DD#
PD (122)	0.12	2.909	0.228	0.12	0.635	0.723	0.39	1.471	0.479
MD (229)	0.13			0.10			0.37
WD (17)	0.03			0.09			0.28
Regional lymph node&
positive (104)	0.13	0.111	0.739	0.09	0.377	0.539	0.36	0.419	0.518
negative (226)	0.14			0.10			0.39
Clinicopathological stage#
early (39)	0.17	0.761	0.683	0.08	0.996	0.608	0.47	4.387	0.112
moderate (195)	0.14			0.11			0.37
late (80)	0.13			0.09			0.34

^aMinor allele (A) frequency of rs17533090 in cases;

^bMinor allele (G) frequency of rs35399661 in cases;

^cMinor allele (A) frequency of rs3763338 in cases;

^dMinor allele (G) frequency of rs2844695 in cases;

MT: medullary type; UT: ulcerative type, ST: scirrhous type;

FT: fungating type;

DD: degree of differentiation;

PD: poorly-differentiated;

MD: moderate-differentiated;

WD: well-differentiated.

^#df = 2; *df = 3; ^&df = 1