Table 5. Relationship of HLA-DQA1 protein immunostaining and clinical characteristics of ESCC.
Clinical characteristics | N | Positive staining n (%) | ?2 | P | OR (95%CI) |
Gender# | |||||
Male | 22 | 14 (63.6) | 0.622 | 0.430 | 0.61 (0.18–2.08) |
Female | 27 | 20 (74.1) | |||
Age# | |||||
≤60 | 25 | 12 (48) | 10.992 | 0.001 | 0.08 (0.02–0.44) |
>60 | 24 | 22 (91.7) | |||
Family history# | |||||
positive | 39 | 7 (17.9) | 20.856 | 0.000 | 0.10 (0.03–0.28) |
negative | 39 | 27 (69.2) | |||
Area* # | |||||
HIA | 37 | 27 (73.0) | 0.914 | 0.339 | 0.52 (0.13–2.02) |
LIA | 12 | 7 (58.3) | |||
Regional lymph node# | |||||
positive | 13 | 7 (53.8) | 1.467 | 0.226 | 1.86 (0.48–7.23) |
negative | 36 | 26 (72.2) | |||
Tumor location& | |||||
upper thoracic | 9 | 8 (88.9) | 1.453 | 0.528 | / |
middle thoracic | 31 | 22 (71.0) | |||
lower thoracic | 3 | 2 (66.7) |
* HIA: high-incidence area; LIA: low-incidence area.
df = 1; &df = 2.