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. 2014 Mar 4;9(3):e90438. doi: 10.1371/journal.pone.0090438

Table 5. Relationship of HLA-DQA1 protein immunostaining and clinical characteristics of ESCC.

Clinical characteristics N Positive staining n (%) ?2 P OR (95%CI)
Gender#
Male 22 14 (63.6) 0.622 0.430 0.61 (0.18–2.08)
Female 27 20 (74.1)
Age#
≤60 25 12 (48) 10.992 0.001 0.08 (0.02–0.44)
>60 24 22 (91.7)
Family history#
positive 39 7 (17.9) 20.856 0.000 0.10 (0.03–0.28)
negative 39 27 (69.2)
Area* #
HIA 37 27 (73.0) 0.914 0.339 0.52 (0.13–2.02)
LIA 12 7 (58.3)
Regional lymph node#
positive 13 7 (53.8) 1.467 0.226 1.86 (0.48–7.23)
negative 36 26 (72.2)
Tumor location&
upper thoracic 9 8 (88.9) 1.453 0.528 /
middle thoracic 31 22 (71.0)
lower thoracic 3 2 (66.7)

* HIA: high-incidence area; LIA: low-incidence area.

#

df = 1; &df = 2.