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. 2014 Mar 4;9(3):e90476. doi: 10.1371/journal.pone.0090476

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© 2014 Tang et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(a) Negative Galectin-1 expression in normal pancreas tissue. (b) Weak Galectin-1 expression in the stromal of chronic pancreatitis tissue. (c–e) Strong Galectin-1 expression in stromal cells of pancreatic cancer tissue, and increased from well (c), moderately (d) to poorly (e) differentiated pancreatic cancer. (f) Quantification of mean density of Galectin-1 expression in different pancreatic tissues. *p<0.01 vs. well, ^# p<0.05 vs. well, ^△ p<0.05 vs. MR. NP, normal pancreas; CP, chronic pancreatitis; Well, Well differentiated pancreatic cancer; MR, moderately differentiated pancreatic cancer; Poorly, poorly differentiated pancreatic cancer. Original magnification: ×200. (g) Galectin-1 expression was negative in non-metastatic peripancreatic lymph nodes. (h) Galectin-1 positive staining was found in metastatic peripancreatic lymph nodes. (i) Quantification of mean density of Galectin-1 expression in non-metastatic and metastatic peripancreatic lymph nodes. *P<0.01 vs. negative.