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Paraxial mesoderm is intact in Tcf4−/−/Tcf1−/− embryos. Whole-mount in situ hybridizations of E10.5 littermates using markers for paraxial mesoderm. (A, C, E) Tcf4+/−/Tcf1−/− embryos and (B, D, F) Tcf4−/−/Tcf1−/− embryos. Panels A and B show stainings for Paraxis, panels C and D show Pax1 stainings. Panels E and F show expression of Myf5. All three somitic markers confirm the presence of paraxial mesoderm throughout the axis of Tcf4−/−/Tcf1−/− mutants.
