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. 2014 Mar 4;9(3):e90608. doi: 10.1371/journal.pone.0090608

Figure 3. Fibrogenesis in the liver of HBV transgenic mice.

Figure 3

(A) Entire collagen was assessed by measurement of hydroxyproline (HYP) in murine liver (mean±SEM, n = 5–10). (B) Activation of hepatic stellate cells in HBV transgenic mice. Paraffin-embedded liver sections of 26-week-old HBVTg/c mice were analysed using anti-GFAP (left panel) and anti-Desmin (right panel) antibodies. Inserts - immunohistochemical analysis of the liver from wild-type BALB/c mouse. 100× - original magnification 100×, bar  = 200 µm. 200× – original magnification 200×, bar  = 200 µm.