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. 2014 Mar 4;9(3):e90608. doi: 10.1371/journal.pone.0090608

Table 1. Selected hepatic genes significantly differentially expressed in the liver of 12-week-old HBV transgenic mice.

Accession Primary Sequence Name Sequence Description Fold Change HBVTg/c Fold Change HBVTg/6
NM_019738 Nupr1 Nuclear protein 1 14.97 5.44
NM_007498 Atf3 Activating transcription factor 3 9.53 3.25
NM_007837 Ddit3 DNA-damage inducible transcript 3 6.39 2.14
NM_024440 Derl3 Der1-like domain family, member 3 8.52 1.44
NM_016773 Nucb2 Nucleobindin 2 4.16 1.81
NM_012055 Asns Asparagine synthetase 4.14 2.28
NM_007836 Gadd45a Growth arrest and DNA-damage-inducible 45 alpha 2.61 1.07
NM_144554 Trib3 Tribbles homolog 3 2.18 −1.13
NM_013560 Hspb1 Heat shock protein 1 2.14 2.01
NM_022310 Hspa5 Heat shock 70 kD protein 5 (GRP78) 2.08 1.19
NM_011631 Hsp90b1 Heat shock protein 90 kDa beta (Grp94) 1.91 −1.05
NM_011817 Gadd45g Growth arrest and DNA-damage-inducible 45 gamma −1.67 2.18
NM_010591 Jun Jun oncogene 4.17 2.30
NM_008182 Gsta2 Glutathione S-transferase, alpha 2 (Yc2) 3.20 2.04
NM_031170 Krt2-8 Keratin complex 2, basic, gene 8 2.21 1.95
NM_007742 Col1a1 Procollagen, type I, alpha 1 2.00 1.48
NM_007743 Col1a2 Procollagen, type I, alpha 2 1.94 1.23
NM_011594 Timp2 Tissue inhibitor of metalloproteinase 2 1.75 −1.04
NM_010664 Krt1-18 Keratin complex 1, acidic, gene 18 1.81 1.80