Skip to main content
. 2014 Feb 17;5:13. doi: 10.1186/2040-2392-5-13

Figure 3.

Figure 3

Independent replication of genome-wide significant linkage at 20p13. Genome-wide significant linkage signal at 20p13 from the combined sample (ALL fams; green, solid line), Autism Genetics Resource Exchange families (AGRE fams) analyzed by Weiss et al.[33] (orange, dashed line), and all AGRE families not previously analyzed by Weiss et al. [33] (Ind. Fams; purple, solid line). Top: linkage across the full chromosome 20; middle: linkage across a 2-logarithm of odds (LOD) interval from the peak LOD; bottom: RefSeq gene alignment in the 2-LOD interval. Dashed lines mark LOD thresholds corresponding to linkage P-values of 0.01, 0.001, and 0.0001 [35].