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. 2014 Mar 5;34(10):3467–3474. doi: 10.1523/JNEUROSCI.3861-13.2014

Figure 1.

Figure 1.

Group mean (+SEM) start latencies (top), run times (middle), and retreat frequencies (bottom) of rats running an alley for a single daily intravenous injection of 1.0 mg/kg/0.1 ml cocaine over 15 trials. Scores have been averaged across 3 d bins. Each runway trial was preceded by bilateral intracranial infusion of either the “Low Dose” (0.5 nmol/0.5 μl/side) or the “High Dose” (1.0 nmol/0.5 μl/side) of the NE β-antagonists (betaxolol + ICI 118551) or “Vehicle” delivered directly into either the CeA or BNST. This figure thus illustrates the data from 5 groups of animals: CeA High Dose (n = 9), CeA Low Dose (n = 7), BNST High Dose (n = 7), BNST Low Dose (n = 9), and the combined Vehicle group (n = 20).