Figure 1.

CIE exposure resulted in deficits in performance on an operant set-shifting task. Rats were tested 1 week after the last day of ethanol exposure. A, Control and CIE animals performed the visual-cue discrimination equally well both before and after CIE/air exposure. B, CIE-exposed rats required significantly more trials compared with control rats to change their response strategy to the new task rule. C, The increase in the number of trials required to shift to the new rule was associated with a significant increase in the number of response errors. n = 9 controls and n = 7 CIE rats. D, Control and CIE-exposed rats showed equal reward motivation when tested on a PR responding procedure. *p < 0.05 for all comparisons, n = 8 controls and n = 8 CIE rats.