. Author manuscript; available in PMC: 2015 Feb 1.

Published in final edited form as: Curr Opin Microbiol. 2013 Dec 22;0:61–66. doi: 10.1016/j.mib.2013.11.008

Table 1.

Cell tropism and vacuolar escape determinants of cytosolic bacteria.

Genus	Gram +/−	Cell tropism	Vacuolar escape determinants, bacterial
Burkholderia	−	Mφ, PMN, epithelial cells	T3SS_BSA
Shigella	−	Mφ, DC, intestinal epithelial cells	Mxi-Spa T3SS, IpaB
Francisella	−	Mφ, PMN, DC, epithelial cells, hepatocytes	IglC, MglA, FTT11103
Listeria	+	Mφ, intestinal epithelial	LLO, phospholipase C
Rickettsia	−	Vascular endothelial, Mφ	Phospholipases, hemolysin
Mycobacterium	Acid-fast +	Mφ	ESX-1 T7SS, ESAT-6