The level of cytokines/chemokines in sera of the study groups. (A) TNF-α. (B) CCL17. (C) IL-2. Short horizontal lines in each group indicate median values. The asterisk symbols (*, **, ***, and ****) are indicating of P<0.05, P<0.01, P<0.001, and P<0.0001, respectively. TNF-α, tumor necrosis factor alpha.