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. 2014 Mar 7;20(9):2397–2402. doi: 10.3748/wjg.v20.i9.2397

Table 2.

Genotype distributions and allele frequencies of the studied polymorphisms in patients and controls, and their risk prediction for Crohn's disease under three genetic models of inheritance

Polymorphism Patients (n = 312) Controls (n = 479) P (χ2) Genetic models OR; 95%CI
rs1800624 TT 248 343 Additive 0.64; 0.47-0.88
AT 62 123 0.012 Dominant 0.65; 0.46-0.91
AA 2 13 Recessive 0.23; 0.05-1.03
A 10.6% 15.6% 0.005
rs1800625 TT 228 353 Additive 0.98; 0.73-1.33
CT 82 118 0.460 Dominant 1.03; 0.75-1.42
CC 2 8 Recessive 0.38; 0.08-1.80
C 13.8% 14.0% 0.940
rs2070600 GG 174 303 Additive 1.29; 1.03-1.62
AG 112 148 0.086 Dominant 1.37; 1.02-1.83
AA 26 28 Recessive 1.46; 0.84-2.55
A 26.3% 21.3% 0.022

OR: Odds ratio.