Table 1.

Network parameters. The table contains some important characteristics of the network (see text for more detailed description). The second column contains the network parameters for the whole network while the third column contains the network parameters for the network where the 20 most promiscuous compounds have been removed. The average path length (D) is determined by taking the average over the MPLs between all vertex pairs. The connectivity of a vertex is defined as the number of vertices which it is connected to by an outgoing edge.

NETWORK PARAMETERS	0 COMPOUNDS REMOVED	20 COMPOUNDS REMOVED
Number of vertices (u)	1,172	1,172
Number of edges (k)	224,972	11,365
Mean connectivity ()	192	9.7
Connectivity standard deviation	151	10
Average path length (D)	1.9	4.2
Average path length (random network) (Dr)	1.3	3.0
Clustering coefficient (Cn)	0.72	0.48
Clustering coefficient (random network) (Cr)	0.16	0.0074