Table 2.

The most promiscuous compounds in the network. The frequency of a compound is the number of times the compound occurs as part of an edge in the network.

RANK	COMPOUND	FREQUENCY
1	H2O	79,485
2	ATP	46,579
3	H+	27,033
4	Mg2+	26,384
5	ADP	23,954
6	Orthophosphate	23,189
7	Pyridoxal phosphate	10,091
8	NAD	7,710
9	NADH	5,742
10	CO2	4,245
11	Pyruvate	4,130
12	NADP	3,638
13	NADPH	3,284
14	AMP	2,964
15	NH3	2,692
16	Coenzyme A	2,638
17	L-Glutamate	2,302
18	Acetyl-CoA	982
19	Phosphoenolpyruvate	941
20	O2	920
21	2-Ketoglutarate	808
22	Mn2+	650
23	S-Adenosylmethionine	454
24	L-Aspartate	408
25	FAD	378
26	Fructose-6-phosphate	312
27	GAP	277
28	Zn2+	272
29	Sucrose	272
30	K+	268