Table 3.

Summary of Homozygous Blocks Identified in Six Families with LCA

Family	Chr	Start	End	Length
KKESH2	10	4,692,299	28,687,145	23,994,846
	10	95,392,963	119,610,549	24,217,586
	2	67,335,826	87,175,553	19,839,727
	2	94,759,484	100,814,358	6,054,874
	2	237,371,678	242,692,820	5,321,142
	13	74,774,390	97,207,720	22,433,330
	4	844,712	6,374,355	5,529,643
	4	13,417,458	48,967,354	35,549,896
	6	5,767,191	13,849,594	8,082,403
	6	22,303,479	42,929,919	20,626,440
	16	13,703,368	21,234,774	7,531,406
	7	102,176,469	130,176,130	27,999,661
	8	103,136,803	121,252,831	18,116,028
KKESH72	2	71,564,649	74,339,404	2,774,755
KKESH24	1	27,535,253	43,222,769	15,687,516
	20	53,239,401	59,936,745	6,697,344
	3	104,855,337	104,877,189	21,852
	3	122,757,953	129,806,851	7,048,898
	7	106,234,136	126,577,422	20,343,286
KKESH28	1	185,439,838	200,728,605	15,288,767
	1	200,745,815	206,592,720	5,846,905
	11	134,433,812	134,435,899	2,087
	3	118,133,470	169,824,936	51,691,466
	12	5,363,096	19,757,396	14,394,300
	21	28,327,299	28,339,633	12,334
	21	41,134,108	46,919,231	5,785,123
	13	75,079,282	89,305,858	14,226,576
	6	23,674,393	41,934,989	18,260,596
	16	6,564,364	8,538,170	1,973,806
	8	111,858,228	140,521,054	28,662,826
	17	46,238,130	60,493,874	14,255,744
KKESH88	1	155,091,425	178,231,760	23,140,335
	20	11,799	5,655,548	5,643,749
	21	31,374,803	40,419,896	9,045,093
	3	97,652,153	129,099,032	31,446,879
	13	46,193,917	71,963,849	25,769,932
	5	107,956,758	112,004,899	4,048,141
	7	146,181,172	151,027,186	4,846,014
KKESH34	11	54,631,614	91,827,532	37,195,918

The homozygous regions are shared by affected members and are either heterozygous or are not present in unaffected members. The coordinates are based on Human March 2006 (NCBI36/hg18) Assembly.