Table IV.
The relationship between haplotype of Adiponectin and insulin two polymorphisms in the two study groups
|
PCOS
|
Controls
|
|||||||||||||||||||
| TA (n=63) | TC (n=81) | GA (n=29) | GC (n=13) | p-value | TA (n=48) | TC (n=62) | GA (n=29) | GC (n=17) | p-value | |||||||||||
| Haplotype adiponectin | ||||||||||||||||||||
| Body mass index (kg/m 2) | 26.6±4. 9 | 26.6±7.31 | 27.6±6.16 | 26.7±7.91 | 0.91 | 25.00±4.03 | 26.00±4.65 | 25.7±4.95 | 24.3±3.71 | 0.46 | ||||||||||
| PCO- severity score | 9.13±3 | 9.15±2.88 | 29.0±2.71 | 9.23±1.69 | 0.90 | 3.48±1.20 | 3.26±0.60 | 3.24±0.69 | 3.29±0.59 | 0.53 | ||||||||||
| Systolic (mmHg) | 107±11.6 | 9.15±2.88 | 109±13.0 | 108±11.1 | 0.14 | 108±11 | 109±13.3 | 106±10.7 | 108±10.1 | 0.80 | ||||||||||
| Diastolic (mmHg) | 69.2±8.7 | 67.1±10.6 | 69.1±10.2 | 73.5±10.9 | 0.11 | 67.6±8. 9 | 68.5±9.2 | 65.5±9.1 | 68.8±9.9 | 0.50 | ||||||||||
| Waist Circumferences (m) | 0.87±0.11 | 0.86±0.13 | 0.89±0.14 | 0.9 ±0.17 | 0.52 | 0.85±0.09 | 0.88±0.09 | 0.85±0.1 | 0.8. ±0.07 | 0.03 | ||||||||||
| Hip Circumferences (m) | 1.04±0.08 | 1.02±0.10 | 1.05±0.12 | 1.05±0.14 | 0.64 | 1.00±0.08 | 1.01±0.14 | 1.01±0.09 | 0.99±0.07 | 0.91 | ||||||||||
| WHR® | 0.8±0.1 | 0.8±0.07 | 0.8±0.06 | 0.8±0.06 | 0.70 | 0.8±0.05 | 0.1±0.9 | 0.83±0.05 | 0.8±0.04 | 0.56 | ||||||||||
| HOM-IRα | 1.2(0.7-1.9) | 1.1(0.7-1.8) | 1.2(0.5-2) | 0.8(0.5-2) | 0.37● | - | - | - | - | - | ||||||||||
| LH/FSH | 2.4(1.2-3.4) | 2.1(1.7-3.5) | 3.7(1.5-8) | 1.6(0.7-2) | 0.95● | - | - | - | - | - | ||||||||||
| PCOS | Controls | |||||||||||||||||||
| CA (n=62) | CG (n=52) | TA (n=48) | CG (n=24) | p-value | CA (n=61) | CG (n=34) | TA (n=37) | CG (n=24) | p-value | |||||||||||
| Haplotype Insulin | ||||||||||||||||||||
| Body mass index (kg/m 2) | 27.1±6.7 | 26.4±7.2 | 26.9±5.4 | 26.3±6.1 | 0.90 | 25.4±4.2 | 24.2±3.4 | 26.4±5.1 | 25.9±4.9 | 0.20 | ||||||||||
| PCO- severity score | 9.5±2.9 | 9.13±2.9 | 8.64±2.5 | 9.58±2.9 | 0.44 | 3.3±0.7 | 3.2±0.4 | 3.3±1.1 | 3.4±1.02 | 0.66 | ||||||||||
| Systolic (mmHg) | 105±11.7 | 106±11.8 | 107±12.9 | 105±13.9 | 0.60 | 106±11.9 | 109±12.5 | 110±11.7 | 108±10.7 | 0.31 | ||||||||||
| Diastolic (mmHg) | 67.1±9.9 | 68.5±9.1 | 70.9±10.9 | 67.6±1 | 0.23 | 66.2±8.9 | 67.1±9.06 | 69.7±8.9 | 69.6±9.7 | 0.20 | ||||||||||
| Waist (m | 0.87±0.14 | 0.86±0.12 | 0. 9±0.13 | 0.85±0.12 | 0.62 | 0.86±0.09 | 0.83±0.08 | 0.87±0.11 | 0.87±0.09 | 0.31 | ||||||||||
| Hip (m) | 1.05±0.12 | 1.02±0.9 | 1.04±0.10 | 1.02±0.11 | 0.60 | 1.01±0.08 | 0.99±0.05 | 1.01±0.08 | 0.99±0.22 | 0.74 | ||||||||||
| WHR® | 0.8±0.1 | 0.84±0.1 | 0.85±0.1 | 0.8±0.07 | 0.47 | 0.85±0.06 | 0.83±0.05 | 0.85±0.06 | 1.2±1.6 | 0.11 | ||||||||||
| HOM-IRα | 2.2(1.7-5) | 2.4(1.5-3.1) | 2.7(2-3.6) | 2.2(0.7-5.5) | 0. 83● | - | - | - | - | - | ||||||||||
| LH/FSH | 0.9(0.5-1.5) | 1.3(0.8-2.3) | 1.1(0.5-1.7) | 1.8(0.8-1.6) | 0.30● | - | - | - | - | - | ||||||||||
One-way ANOVA ●Mann-Whitney αHomeostasis Model of Assessment - Insulin Resistance, ® Waist to hip ratio