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. 2004 Mar 3;4:5. doi: 10.1186/1471-2458-4-5

Table 3.

Autistic Children with or without Regression (N = 1791)

Regression

No (N = 136) Yes (N = 43) P
N % N %
Male Sex 114 83.8 32 74.4 .166
Birth year 1973 – 1977 8 5.9 3 7.0 .789(trend)
1978 – 1982 12 8.9 3 7.0
1983 – 1987 31 23.0 12 27.9
1988 – 1992 56 41.5 12 27.9
1993 – 1997 28 20.7 13 30.2
Past or current epilepsy 21 15.4 7 16.3 .895
Overall level of language2 Mute 21 15.9 10 23.3 .065 (trend)
Single words 27 20.5 11 25.6
Few phrases 28 21.2 11 25.6
Phrase speech 56 42.4 11 25.6
Estimated intellectual functioning Normal IQ 35 27.8 7 17.5 .054 (trend)
Mild MR 61 48.4 17 42.5
Moderate MR 22 17.5 12 30.0
Severe MR 8 6.3 4 10.0
Age of parental recognition (months) 0 – 12 45 43.3 15 35.7 .897 (trend)
13 – 24 45 43.3 23 54.8
25 – 36 12 11.5 4 9.5
36+ 2 1.9 - -
Language delay Yes probable/definite 122 97.6 40 93.0 .163
Regression

No (N = 136) Yes (N = 43) P
N Mean SD N Mean SD

Age at first GPRD diagnosis (years) 127 5.39 4.01 40 5.63 4.29 .746
Age at first letter (years) 133 3.66 2.75 41 2.76 1.02 .002
Age at last report on note (years) 134 10.61 5.65 42 10.15 5.56 .646
Mean number of DSM-IV PDD symptoms
 –Total 136 7.51 3.94 43 8.35 3.67 .221
 –Language/communication 136 2.08 1.43 43 2.37 1.29 .236
 –Social interaction 136 3.04 1.66 43 3.14 2.02 .738
 –Repetitive behaviours 136 2.40 1.73 43 2.84 1.68 .144

1: Autism children only. One child had no information about regression. 2: Mean age when language was recorded was: 7.65 years (SD: 4.39).