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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Biomaterials. 2013 Jul 26;34(33):8213–8222. doi: 10.1016/j.biomaterials.2013.07.033

Fig. 6. Capture and retention of MSC-PPG-19Fc[FUT7+]s on stimulated HUVECs upon varying wall shear stress.

Fig. 6

A. 5×106 MSCs/mL were perfused over stimulated HUVECs at various wall shear stresses. Greater number of MSC-PPG-19Fc[FUT7+] cells captured/tethered onto HUVECs compared to either unmodified MSCs or MSC-PPG cells up to 4 dyn/cm2. Data are mean ± SD for three independent experiments. B. 5×106 MSCs/mL were incubated with stimulated HUVEC monolayers under static conditions for 10 min. The applied wall shear stress was then step increased in 3 min intervals at each shear stress until a final wall shear stress of 10 dyn/cm2 was achieved between 12-15 min. MSC-PPG-19Fc[FUT7+] cells, but not other cell types, were robustly retained at all shear stresses. Data are mean ± SD for four independent experiments. * P < 0.01 with respect to MSC or MSC-PPG cells.