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Plasma hIL-10 concentrations after intrathymic injections of Adv/hIL-10. Time and dose dependent decreases of systemic hIL-10 in A) C57BL6 wild-type and B) IL-10 null (IL-10−/−) mice after intrathymic injection of Adv/hIL-10.Ø Plasma concentrations of hIL-10 in animals treated with Adv/hIL-10 at a dose of 105 particles were below the detection level of the assay throughout all three time-points after injection.
