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. Author manuscript; available in PMC: 2014 Mar 5.
Published in final edited form as: Scand J Immunol. 2008 Oct 8;68(6):565–571. doi: 10.1111/j.1365-3083.2008.02176.x

Figure 6.

Figure 6

Caspase-3 activity is significantly reduced by therapeutic endogenous expression of human IL-10 in thymus of septic IL-10 knockout mice. Compared to animals pretreated with either an empty vector or buffer only, IL-10−/− mice receiving an intrathymic injection with Adv/hIL-10 prior to CLP demonstrated a significant reduction of thymic caspase-3 activity. *P < 0.05 as determined by Student’s t-test (Adv/hIL-10 versus Adv/empty). *P < 0.05 as determined by Student’s t-test (Adv/hIL-10 versus buffer).