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. 2014 Feb 13;2014:309151. doi: 10.1155/2014/309151

Figure 2.

Figure 2

Effect of recombinant klotho (rKl) on the sensitivity of the baroreflex in STZ-diabetic rats. The effect of rKl or rat IgG (IgG) on the mean arterial pressure (MAP, mmHg), heart rate (HR, bpm), and baroreflex sensitivity (BRS, bpm/mmHg) in response to phenylephrine (PE, 8 μg/kg, IV) (a) or (SNP, 50 μg/kg, IV) (b) in each group; Con means control, STZ shows STZ-diabetic rats, STZ + IgG is IgG-treated group and STZ + rKl indicates the recombinant klotho-treated STZ group. The quantification is indicated as the means with the SE (n = 8 per group) in each column shown in the lower panel. **P < 0.01 and ***P < 0.001 compared to Wistar.