Table 1.
Baseline level of the blood glucose, mean arterial pressure (MAP) and heart rate (HR), bradycardic and tachycardic peak, and HR range in STZ rats receiving rat IgG (IgG) or recombinant klotho (rKl).
| Variable | Wistar | STZ | STZ + IgG | STZ + rKl |
|---|---|---|---|---|
| Blood glucose (mg/dL) | 103 ± 4.3 | 363 ± 13.6*** | 362 ± 9.1*** | 368 ± 5.4*** |
| MAP (mmHg) | 112.8 ± 3.17 | 89.2 ± 2.74** | 91.4 ± 3.82** | 104.9 ± 7.21# |
| HR (bpm) | 343 ± 7.2 | 281 ± 5.4*** | 283 ± 8.2*** | 308 ± 9.4# |
| Bradycardic peak (bpm) | 243 ± 4.3 | 247 ± 7.2 | 243 ± 5.8 | 248 ± 4.7 |
| Tachycardic peak (bpm) | 442 ± 7.6 | 352 ± 7.4** | 347 ± 6.6** | 426 ± 5.4## |
| HR range (bpm) | 194 ± 6.8 | 103 ± 8.7*** | 102 ± 5.3*** | 173 ± 8.9## |
Values (mean ± SE) were obtained from each group of eight rats. *P < 0.05, **P < 0.01, and ***P < 0.001 compared to Wistar. # P < 0.05 and ## P < 0.01 compared to STZ.