Table 1.
Patient characteristics based on intended renal replacement modality
| Variable | HD (89) | HHD (21) | PD (154) | Conservative/undecided (35) | Total (299) | P value |
|---|---|---|---|---|---|---|
| Age, years (SD) |
72.1 (11.2) |
63.1 (10.1) |
68.2 (12.9) |
69.5 (12.9) |
69.1 (12.4) |
0.012 |
| Males, n (%) |
59 (66.3) |
15 (71.4) |
82 (53.2) |
22 (62.9) |
178 (59.5) |
0.13 |
| Diabetes mellitus, n (%) |
59 (66.3) |
11 (52.4) |
95 (61.7) |
20 (57.1) |
185 (61.9) |
0.60 |
| Coronary artery disease, n (%) |
40 (45.5) |
8 (38.1) |
55 (36.9) |
12 (35.3) |
115 (39.4) |
0.58 |
| Previous stroke, n (%) |
20 (23.0) |
1 (4.8) |
24 (15.8) |
8 (22.9) |
53 (18.0) |
0.17 |
| Congestive heart failure, n (%) |
30 (34.5) |
3 (14.3) |
28 (18.4) |
11 (31.4) |
72 (24.4) |
0.02 |
| Weight, kg (SD) |
85.7 (19.2) |
98.2 (31.7) |
84.7 (19.2) |
84.4 (20.7) |
85.9 (21.0) |
0.048 |
| Ethnicity, n (%) |
|
|
|
|
|
|
| Caucasian |
80 (89.9) |
19 (90.5) |
133 (86.4) |
22 (62.9) |
254 (84.9) |
|
| Afro-Canadian |
4 (4.5) |
0 (0) |
8 (5.2) |
5 (14.3) |
17 (5.7) |
0.007 |
| Aboriginal |
2 (2.2) |
2 (9.5) |
2 (1.3) |
3 (8.6) |
9 (3.0) |
|
| Other |
3 (3.4) |
0 (0) |
11 (7.1) |
5 (14.3) |
19 (6.4) |
|
| Creatinine, μmol/L (IQR)a |
512.0 (405.0, 633.0) |
535.0 (441.0, 662.5) |
459.0 (418.0, 562.0) |
622.0 (489.0, 783.0) |
500.0 (418.0, 629.0) |
0.001 |
| eGFR, ml/min/1.73 m2 (SD) |
9.4 (3.4) |
10.1 (5.2) |
9.6 (3.0) |
7.7 (3.6) |
9.4 (3.4) |
0.022 |
| Albumin, g/L (SD) |
35.2 (5.3) |
36.1 (6.4) |
36.4 (4.5) |
34.4 (4.0) |
35.9 (5.0) |
0.092 |
| eGFR decrease, |
|
|
|
|
|
|
| ml/min/1.73 m2/year (IQR)a,b |
3.4 (1.6, 5.8) |
3.6 (1.9, 7.5) |
3.5 (2.2, 5.3) |
4.0 (2.0, 7.3) |
3.5 (1.9, 5.6) |
0.83 |
| Time- entry to decision, days (IQR)a |
162.0 (85.0, 411.5) |
128.0 (50.5, 369.5) |
109.0 (40.5, 223.0) |
157.0 (48.0, 379.0) |
127.0 (49.0, 273.0) |
0.010 |
| Time-decision to initiation, days (IQR)a |
334.0 (137.5, 618.0) |
322.0 (145.5, 855.0) |
325.5 (148.8, 325.5) |
241.0 (66.0, 797.0) |
323.0 (141.0, 731.0) |
0.62 |
| Distance to nearest HD unit, km (IQR)a | 4.6 (2.2, 8.5) | 5.5 (3.6, 10.7) | 5.9 (3.0, 10.3) | 6.4 (2.4, 10.9) | 5.5 (2.6, 9.4) | 0.22 |
Note: Means and standard deviations shown for normally distributed variables. Median and interquartile range values indicated by (a) for non-normally distributed variables. bchange in eGFR multiplied by (-1) based on available values preceding dialysis initiation.
Abbreviations: HD hemodialysis, HHD home hemodialysis, PD peritoneal dialysis, kg kilograms, eGFR estimated glomerular filtration rate based on 4-variable MDRD equation, km kilometers.