Table 2.
Patient characteristics based on first renal replacement modality initiated
| Variable | HD (190) | HHD (14) | PD (95) | Total (299) | P value |
|---|---|---|---|---|---|
| Age, years (SD) |
70.3 (11.6) |
61.9 (10.7) |
67.9 (13.8) |
69.1 (12.4) |
0.024 |
| Males, n (%) |
119 (62.6) |
11 (78.6) |
48 (50.5) |
178 (59.5) |
0.048 |
| Diabetes mellitus, n (%) |
120 (63.2) |
9 (64.3) |
56 (58.9) |
185 (61.9) |
0.77 |
| Coronary artery disease, n (%) |
83 (45.4) |
3 (21.4) |
29 (30.5) |
115 (39.4) |
0.021 |
| Previous stroke, n (%) |
39 (21.0) |
0 (0) |
14 (14.7) |
53 (18.0) |
0.087 |
| Congestive heart failure, n (%) |
61 (32.8) |
0 (0) |
11 (11.6) |
72 (24.4) |
<0.001 |
| Weight, kg (SD) |
87.1 (21.1) |
97.5 (30.6) |
82.0 (18.1) |
85.9 (21.0) |
0.017 |
| Ethnicity, n (%) |
|
|
|
|
|
| Caucasian |
161 (84.7) |
12 (85.7) |
81 (85.3) |
254 (84.9) |
|
| Afro-Canadian |
13 (6.8) |
0 (0) |
4 (4.2) |
17 (5.7) |
0.72 |
| Aboriginal |
6 (3.2) |
1 (7.1) |
2 (2.1) |
9 (3.0) |
|
| Other |
10 (5.3) |
1 (7.1) |
8 (8.4) |
19 (6.4) |
|
| Creatinine, μmol/L (IQR)a |
524.5 (431.8, 524.5) |
624.5 (486.0, 733.5) |
446.0 (398.0, 532.0) |
500.0 (418.0, 629.0) |
<0.001 |
| eGFR, ml/min/1.73 m2 (SD) |
9.2 (3.6) |
8.3 (3.2) |
9.9 (3.0) |
9.4 (3.4) |
0.10 |
| Albumin, g/L (SD) |
35.2 (4.9) |
37.5 (6.2) |
36.8 (4.5) |
35.9 (5.0) |
0.013 |
| eGFR decrease, |
|
|
|
|
|
| ml/min/1.73 m2/year (IQR)a,b |
3.2 (1.7, 5.5) |
5.1 (2.7, 7.4) |
3.7 (2.3, 5.4) |
3.5 (1.9, 5.6) |
0.056 |
| Time- Entry to decision, days (IQR)a |
147.5 (65.0, 359.3) |
241.0 (42.5, 449.0) |
108.0 (39.0, 190.0) |
127.0 (49.0, 273.0) |
0.011 |
| Time-Decision to initiation, days (IQR)a |
391.0 (139.0, 797.3) |
436.0 (135.3, 589.0) |
265.0 (146.0, 519.0) |
323.0 (141.0, 731.0) |
0.38 |
| Distance to nearest HD unit, km (IQR)a | 5.2 (2.5, 9.0) | 5.6 (3.8, 16.5) | 6.1 (3.0, 12.6) | 5.5 (2.6, 9.4) | 0.35 |
Note: Means and standard deviations shown for normally distributed variables. Median and interquartile range values indicated by (a) for non-normally distributed variables. bchange in eGFR multiplied by (-1) based on available values preceding dialysis initiation.
Abbreviations: HD hemodialysis, HHD home hemodialysis, PD peritoneal dialysis, kg kilograms, eGFR estimated glomerular filtration rate based on 4-variable MDRD equation, km kilometers.