. Author manuscript; available in PMC: 2014 Aug 1.

Published in final edited form as: Mol Nutr Food Res. 2013 Jul 4;57(8):1378–1389. doi: 10.1002/mnfr.201200827

Table 4.

Oxylipin levels in serum vs. plasma (nM).

Class	PUFA	Oxylipin	Serum (B¹)		Plasma (HM²)		Plasma (PP³)

			Av⁴	SD⁵	Av	SD	Av	SD

ω-3	ALA	9-HOTrE	0.71	0.61	1.98	0.12	1.19	0.91
		13-HOTrE	0.80	0.72	1.9	0.21	1.11	0.74
		15(16)-EpODE	3.9	3.2	3.27	0.23	2.77	2.1
		15,16-DiHODE	7.1	3.3	14.5	1	5.93	2.4
	EPA	12-HEPE	2.4	7.0	3.19	0.35	0.195	0.11
		15-HEPE	0.07	0.09	0.28	1.63	1.63	1.6
		11,12-DiHETE	0.04	0.03	NR⁶	-⁷	NR	-
		14,15-DiHETE	0.07	0.03	ND⁸	-	0.304	0.1
		17,18-DiHETE	0.47	0.23	14.4	1.1	2.08	0.85
	DHA	10(11)-EpDPE	0.25	0.19	NR	-	NR	-
		4,5-DiHDPE	0.79	0.62	NR	-	NR	-
		10,11-DiHDPE	0.19	0.13	NR	-	NR	-
		13,14-DiHDPE	0.22	0.14	NR	-	NR	-
		16,17-DiHDPE	0.30	0.15	NR	-	NR	-
ω-6	LA	9,12,13-TriHOME	3.5	2.3	0.827	21	4.11	2.2
		9,10,13-TriHOME	1.7	1.0	0.513	0.083	1.16	0.64
		9-HODE	13	10	11.7	0.23	11	6.1
		13-HODE	23	18	47.3	0.53	58.2	28
		9-KODE	2.9	3.5	2.41	0.29	5.3	2.7
		9,10-DiHOME	3.7	2.7	60.5	3.8	29.7	11
		12,13-DiHOME	6.8	4.1	7.69	0.59	5.82	3
		9(10)-EpOME	4.1	4.1	2.17	0.23	5.47	7.4
		12(13)-EpOME	6.1	5.7	4.88	0.34	7.21	8.8
	DGLA	15-HETrE	0.67	0.67	0.437	0.028	0.732	0.45
	AA	PGE2	0.34	0.85	0.0967	0.012	0.172	0.13
		TXB2	3.1	4.3	0.865	0.18	0.919	1.6
		5-HETE	1.7	1.8	0.901	0.029	1.02	0.79
		8-HETE	0.55	1.3	2.09	0.16	0.536	0.4
		11-HETE	0.77	1.5	0.425	0.0095	0.401	0.36
		12-HETE	43	72	6.42	0.74	3.95	3.3
		15-HETE	2.0	2.6	1.8	0.098	2.04	1.2
		12-KETE	4.0	6.2	<0.1	-	<0.1	-
		15-KETE	0.39	0.90	0.749	0.08	0.682	0.76
		5(6)-EpETrE	0.51	0.45	NR	-	NR	-
		8(9)-EpETrE	0.37	0.35	<0.2	-	0.627	0.71
		11(12)-EpETrE	0.43	0.58	0.303	0.028	1.02	1.4
		14(15)-EpETrE	0.48	0.67	1.77	0.05	0.442	0.59
		5,6-DiHETrE	0.29	0.19	0.264	0.025	0.189	0.092
		8,9-DiHETrE	0.31	0.23	0.294	0.056	0.244	0.078
		11,12-DiHETrE	0.75	0.47	0.779	0.037	0.566	0.2
		14,15-DiHETrE	0.91	0.61	0.714	0.031	0.603	0.18

Baseline values (prior to ω-3 supplementation)

Human Metabolome (n=3 individuals). Data are from Psychogios et al. [39].

Pennington Plasma (n=70 individuals). Data are from Psychogios et al. [39].

⁴

Average

⁵

Standard deviation

⁶

Not reported

⁷

No value

⁸

Not detected