Table 1.
Mice | 11-cis-retinal (pmol/eye) | n (total eyes) |
---|---|---|
Rho+/+ | 171 ± 25.1 | 4 (14) |
Rho+/− | 89.5 ± 13.9 | 5 (26) |
RhoP23H/+ | 89.8 ± 7.6 | 3 (16) |
aAmounts of 11-cis-retinal in dark adapted eyes were analyzed by normal phase high-performance liquid chromatography (HPLC). There was no significant difference in 11-cis-retinal content between Rho+/− and RhoP23H/+ mice at PND14. Consistent with the single Rho+/+ allele, the amount of 11-cis-retinal in Rho+/− and RhoP23H/+ mice was about half of that in Rho+/+ mice. Values are means ± SD. n, number of repeated analyses.