Table 2.
Chromosome | Rsid | Position (hg19) | Gene | Risk allele | P MS | OR MS | P ALS | OR ALS |
---|---|---|---|---|---|---|---|---|
1 | rs4648356 | 2709164 | MMEL1 (TNFRSF14) | C | 0.012 | 1.09 | 0.97 | 1.00 |
1 | rs11810217 | 93148377 | EVI5 | T | 0.00032 | 1.14 | 0.12 | 0.94 |
1 | rs11581062 | 101407519 | SLC30A7 | G | 0.032 | 1.08 | 0.025 | 1.08 |
1 | rs1335532 | 117100957 | CD58 | A | 1.2E-08 | 1.35 | 0.97 | 1.00 |
1 | rs1323292 | 192541021 | RGS1 | A | 0.0098 | 1.11 | 0.53 | 1.03 |
1 | rs7522462 | 200881595 | C1orf106 | G | 0.00083 | 1.13 | 0.023 | 0.92 |
2 | Rs6718520a (4) | 43325570 | ZFP36L2 (THADA) | A | 1.2E-05 | 1.16 | 0.84 | 1.01 |
2 | rs12466022 | 43359061 | ZFP36L2 (THADA) | C | 4.2E-05 | 1.16 | 0.76 | 0.99 |
2 | rs7595037 | 68647095 | PLEK | T | 1.6E-05 | 1.15 | 0.32 | 0.97 |
2 | rs17174870 | 112665201 | MERTK | C | 0.00012 | 1.15 | 0.79 | 1.01 |
2 | rs10201872 | 231106724 | SP140 | T | 0.00056 | 1.15 | 0.13 | 1.07 |
3 | rs669607 | 28071444 | intergenic | C | 2.5E-05 | 1.15 | 0.57 | 0.98 |
3 | rs2028597 | 105558837 | CBLB | G | 0.56 | 1.03 | 0.52 | 1.04 |
3 | rs2293370 | 119219934 | C3orf1 | G | 0.056 | 1.08 | 0.29 | 0.96 |
3 | rs9282641 | 121796768 | CD86 | G | 0.0015 | 1.22 | 0.52 | 0.96 |
3 | rs2243123 | 159709651 | IL12A | C | 0.17 | 1.05 | 0.25 | 1.04 |
4 | rs228614 | 103578637 | MANBA | G | 0.0092 | 1.18 | 0.23 | 0.625 |
5 | rs6897932 | 35874575 | IL7R | C | 0.0014 | 1.12 | 0.20 | 0.96 |
5 | rs4613763 | 40392728 | PTGER4 | C | 0.00014 | 1.19 | 0.87 | 0.99 |
5 | rs2546890 | 158759900 | IL12B | A | 3.8E-06 | 1.16 | 0.78 | 1.01 |
6 | rs12212193 | 90996769 | BACH2 | G | 0.0055 | 1.09 | 0.14 | 1.05 |
6 | rs802734 | 128278798 | PTPRK | A | 0.0014 | 1.12 | 0.89 | 1.00 |
6 | rs11154801 | 135739355 | AHI1 | A | 0.014 | 1.08 | 0.49 | 0.98 |
6 | rs17066096 | 137452908 | IL22RA2 | G | 0.00096 | 1.13 | 0.29 | 0.96 |
6 | rs1738074 | 159465977 | TAGAP | C | 0.00075 | 1.12 | 0.45 | 0.98 |
7 | rs354033 | 149289464 | ZNF767 | G | 0.00079 | 1.13 | 0.26 | 1.04 |
8 | rs1520333 | 79401038 | PKIA | G | 0.11 | 1.06 | 0.41 | 1.03 |
8 | rs4410871 | 128815029 | MYC | C | 0.018 | 1.09 | 0.54 | 1.02 |
9 | rs2150702 | 5893861 | MLANA | G | 2.5E-05 | 1.14 | 0.015 | 1.08 |
10 | rs3118470 | 6101713 | IL2RA | C | 0.00078 | 1.12 | 0.76 | 1.01 |
10 | rs1250550 | 81060317 | ZMIZ1 | A | 0.0024 | 1.11 | 0.66 | 0.98 |
10 | rs7923837 | 94481917 | HHEX | G | 0.015 | 1.08 | 0.18 | 0.96 |
11 | rs650258 | 60832282 | CD5 | C | 0.00018 | 1.14 | 0.097 | 0.95 |
11 | rs630923 | 118754353 | CXCR5 | C | 0.033 | 1.11 | 0.066 | 1.08 |
12 | rs1800693 | 6440009 | TNFRSF1A | G | NAb | NA | 0.67 | 1.01 |
12 | rs10466829 | 9876091 | CLECL1 | A | 0.0009 | 1.11 | 0.49 | 0.98 |
12 | rs12368653 | 58133256 | AGAP2 | A | 0.0018 | 1.10 | 0.31 | 0.97 |
12 | rs949143 | 123595163 | ARL6IP4 | G | 0.015 | 1.08 | 0.57 | 0.98 |
14 | rs4902647 | 69254191 | ZFP36L1 | C | 0.00022 | 1.12 | 0.72 | 0.99 |
14 | rs2300603 | 76005557 | BATF | T | 0.014 | 1.10 | 0.10 | 0.94 |
14 | rs2119704 | 88487689 | GPR65 | C | 0.045 | 1.13 | 0.23 | 0.93 |
16 | rs2744148 | 1073552 | SOX8 | G | 0.023 | 1.10 | 0.30 | 0.95 |
16 | rs7200786 | 11177801 | CLEC16A | A | 8.8E-05 | 1.14 | 0.58 | 0.98 |
16 | rs13333054 | 86011033 | IRF8 | T | 0.063 | 1.09 | 0.98 | 1.00 |
17 | rs9891119 | 40507980 | STAT3 | C | 0.00016 | 1.13 | 0.86 | 0.99 |
17 | rs180515 | 58024275 | RPS6KB1 | G | 0.093 | 1.06 | 0.74 | 1.01 |
18 | rs7238078 | 56384192 | MALT1 | T | 0.00075 | 1.13 | 0.99 | 1.00 |
19 | rs1077667 | 6668972 | TNFSF14 | C | 0.033 | 1.10 | 0.10 | 0.94 |
19 | rs8112449 | 10520064 | CDC37 | G | 0.14 | 1.05 | 0.83 | 0.99 |
19 | rs874628 | 18304700 | MPV17L2 | A | 0.021 | 1.09 | 0.65 | 0.98 |
19 | rs2303759 | 49869051 | DKKL1 | G | 0.0075 | 1.11 | 0.034 | 1.08 |
20 | rs2425752 | 44702120 | NCOA5 | T | 0.0001 | 1.14 | 0.40 | 0.97 |
20 | rs2248359 | 52791518 | CYP24A1 | C | 0.00085 | 1.12 | 0.29 | 1.04 |
20 | rs6062314 | 62409713 | ZBTB46 | T | 0.047 | 1.14 | 0.52 | 1.04 |
22 | rs2283792 | 22131125 | MAPK1 | G | 0.00036 | 1.12 | 0.23 | 1.04 |
22 | rs140522 | 50971266 | ODF3B | T | 0.0022 | 1.12 | 0.72 | 0.99 |