Table 4.

Minimal Clinically Important Difference (MCID) and Moderate Improvement thresholds in patients with knee symptoms

	Improvement in score Mean (SD)	Relative (%) improvement in score	MDC90
ICOAP Pain (scale 0–100)
Moderate Improvement (=“great deal better”) (N=12)	−26.7 (±14.8)	−60.5%	49.6
MCID Improvement (=“somewhat better”) (N=26)	−18.5 (±22.0)	−31.0%	46.6
ICOAP Constant Pain
Moderate Improvement (=“great deal better”) (N=12)	−29.6 (±14.8)	−68.3%	53.8
MCID Improvement (=“somewhat better”) (N=26)	−18.7 (±24.4)	−32.7%	49.6
ICOAP Intermittent Pain
Moderate Improvement (=“great deal better”) (N=12)	−24.3 (±17.9)	−54.3%	48.7
MCID Improvement (=“somewhat better”) (N=26)	−18.4 (±25.4)	−29.7%	50.8
KOOS-PS (scale 0–100)
Moderate Improvement (=“great deal better”) (N=12)	−15.0 (±16.4)	−32.3%	35.5
MCID Improvement (=“somewhat better”) (N=26)	−2.2 (±17.5)	−4.0%	28.3
KOOS-QOL (scale 0–100)
Moderate Improvement (=“great deal better”) (N=12)	15.6 (±18.8)	35.7%	39.0
MCID Improvement (=“somewhat better”) (N=25)	8.0 (±16.1)	25.7%	29.0

Relative (%) improvement in score was calculated as = 100* (followup score mean−baseline score mean)/baseline score mean