. Author manuscript; available in PMC: 2015 Mar 1.

Published in final edited form as: J Allergy Clin Immunol. 2013 Nov 1;133(3):784–789. doi: 10.1016/j.jaci.2013.09.015

Table 3.

Association of FLG2 variants in the African-American PEER cohort with the persistence of AD, asthma, seasonal allergy and food allergy at study entry. OR = odds ratio; CI = confidence intervals

Variant	OR (95% CI) ADD p-value
Variant	Additive genetic model ^*	Dominant genetic model^*	Asthma⁺	Seasonal allergy⁺	Food allergy⁺
S2377X (rs12568784)	0.44 (0.25, 0.77) p=0.004	0.43 (0.21, 0.88) p=0.022	1.05 (0.70,1.57) p=0.8010	1.01 (0.66,1.56) p=0.625	0.96 (0.84, 1.11) p=0.928
H1249R (rs16833974)	0.23 (0.12, 0.46) p=0.00002	0.23 (0.11, 0.46) p=0.00004	1.12 (0.66,1.90) p=0.677	0.89 (0.48,1.44) p=0.391	0.79 (0.42, 1.47) p=0.451
Q2053del224	0.54 (0.16, 1.80) p=0.234	----	0.88 (0.34,2.32) p=0.804	0.58 (0.23, 1.52) p=0.220	1.42 (0.71, 2.81) p=0.319

GLLAMM model;

⁺

Logistic regression model