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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Kidney Int. 2013 Sep 25;85(3):677–685. doi: 10.1038/ki.2013.359

Table 4.

Change in kidney cortical, medullary, and parenchymal volume by age.

Kidney Volumes Age < 50 years Age ≥ 50 years Test for change in slope before
and after age 50 years*
Cortical Volume cc per decade (p-value) cc per decade (p-value) p-value
  Women −5.6(0.006) −17.7(<0.0001) 0.002
  Men −4.5(0.07) −17.9(0.004) 0.04
Cortical volume per BSA cc/m2 per decade (p-value) cc/m2 per decade (p-value) p-value
  Women −3.7(0.0002) −7.8(<0.0001) 0.04
  Men −3.2(0.002) −9.2(0.001) 0.07
Medullary volume cc per decade (p-value) cc per decade (p-value) p-value
  Women 2.8(0.008) −6.1(0.006) 0.0001
  Men 5.1(0.0004) 0.7(0.83) 0.25
Medullary volume per BSA cc/m2 per decade (p-value) cc/m2 per decade (p-value) p-value
  Women 1.4(0.01) −2.6(0.04) 0.003
  Men 2.0(0.0006) 0.2(0.88) 0.41
Parenchymal volume cc per decade (p-value) cc per decade (p-value) p-value
  Women −2.7(0.32) −22.6(<0.001) 0.0002
  Men 1.4(0.68) −22.7(0.002) 0.004
Parenchymal volume per BSA cc/m2 per decade (p-value) cc/m2 per decade (p-value) p-value
  Women −2.2(0.07) −9.8(<0.001) 0.005
  Men −0.8(0.51) −10.3(0.0008) 0.01
*

Based on modeling age as a linear spline with a knot at age 50 years.