Table 3.
The complete list of the topical and systemic medications including food supplements. Logistic regression was conducted to evaluate the impact of using medications on total retinal blood flow.
| Medications | Glaucoma (n = 30) | Odds ratio per μL/min total RBF (p-value)* | Normal (n = 27) | Odds ratio per μL/min total RBF (p-value)* |
|---|---|---|---|---|
| Systemic beta blockers | 7 | 1.00 (0.82) | 4 | 0.91 (0.09) |
| Calcium channel blockers | 2 | 0.98 (0.76) | 1 | 0.88 (0.22) |
| Diuretics | 1 | 0.95 (0.48) | 2 | 0.97 (0.70) |
| Anti-platelets | 9 | 0.94 (0.11) | 1 | 1.09 (0.49) |
| Diabetes medications | 3 | 0.90 (0.16) | 1 | 1.09 (0.49) |
| Vitamin and mineral supplements | 4 | 0.96 (0.30) | 1 | 1.05 (0.68) |
| Food Supplements | 3 | 1.00 (0.53) | 0 | N/A |
| Anti-lipids | 8 | 0.90 (0.10) | 1 | 1.09 (0.49) |
| Anti-histamines | 1 | 0.93 (0.29) | 0 | N/A |
| Selective serotonin re-uptake inhibitors | 1 | 0.93 (0.29) | 0 | N/A |
| Angiotensin-converting-enzyme inhibitor | 0 | N/A | 2 | 1.00 (0.98) |
| Angiotensin II receptor blockers | 3 | 1.00 (0.87) | 0 | N/A |
| Hypothyroidism medications | 1 | 1.10 (0.49) | 0 | N/A |
| Asthma medications | 2 | 0.80 (0.13) | 1 | 1.07 (0.58) |
| Estrogen | 0 | N/A | 1 | 1.05 (0.68) |
| Pacemaker | 0 | N/A | 1 | 1.12 (0.41) |
| Topical beta blockers | 11 | 1.00 (0.93) | 0 | N/A |
| Prostaglandin analogs | 16 | 1.00 (0.83) | 0 | N/A |
| Alpha 2-adrenergic agonists | 3 | 0.99 (0.98) | 0 | N/A |
| Nonselective adrenergic agonists | 1 | 1.58 (0.29) | 0 | N/A |
| Topical or systemic | ||||
| carbonic anhydrase inhibitors | 7 | 0.97 (0.38) | 0 | N/A |
RBF = retinal blood flow; N/A = not applicable;
Logistic regression analysis (JMP 8.0.2).