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. Author manuscript; available in PMC: 2015 Feb 6.
Published in final edited form as: J Mol Biol. 2014 Feb 6;426(3):570–585. doi: 10.1016/j.jmb.2013.10.025

Fig 6.

Fig 6

Topology of the CcmF and CcmH integral membrane proteins from E. coli. Possible histidine axial ligands to heme are starred (His173=P-His1; His303=P-His2; His261=TM-His1; His491=TM-His2). The highly conserved WWD domain is shaded as are the hydrophobic patches. Completely conserved amino acids (red) were identified by individual protein alignments using CcmF ORFs from selected organisms, as described in (Kranz, Richard-Fogal et al. 2009). Diagram is from (Kranz, Richard-Fogal et al. 2009).