. Author manuscript; available in PMC: 2015 Mar 1.

Published in final edited form as: J Allergy Clin Immunol. 2013 Nov 8;133(3):896–899.e4. doi: 10.1016/j.jaci.2013.08.050

Table 2A.

Comparison of somatic hypermutation frequency in WAS patients and controls

	Transcript	Homology (%)			Mutation frequency (%)			Unmutated sequences (%)
	Transcript	WAS	Ctrl	p-value	WAS	Ctrl	p-value	WAS	Ctrl	p-value
Adult CD21hiCD27+	Cγ VH3	94.35 ± 2.78	93.21 ± 2.16	0.0009	4.94 ± 2.87	6.31 ± 2.75	0.0002	13.98 ± 22.37	4.01 ± 8.68	NS
Adult CD21hiCD27+	Cγ VH4	94.09 ± 2.85	92.77 ± 2.66	0.0009	5.26 ± 2.18	6.82 ± 2.55	0.0001	20.67 ± 22.36	0.617 ± 1.85	0.0149
Children CD21hiCD27+	Cγ VH3	95.65 ± 2.97	94.00 ± 1.53	0.0007	3.51 ± 2.01	4.90 ± 1.78	0.0011	37.01 ± 28.89	0.00	0.0303
Children CD21hiCD27+	Cγ VH4	94.63 ± 2.97	94.83 ± 2.37	NS	4.47 ± 2.69	4.76 ± 2.22	NS	24.57 ± 15.10	6.06 ± 10.49	0.0190