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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Nat Cell Biol. 2014 Feb 9;16(3):245–254. doi: 10.1038/ncb2909

Figure 2. α-catenin inhibits NF-κB signaling in basal-like breast cancer cells.

Figure 2

(a) qPCR of NF-κB response genes in α-catenin-transduced MDA-MB-157 and MDA-MB-436 cells. n = 3 samples per group.

(b) ELISA of TNFα and IL-8 secreted by α-catenin-transduced MDA-MB-157 and MDA-MB-436 cells. n = 3 wells per group.

Data in (a) and (b) are the mean of biological replicates from a representative experiment, and error bars indicate s.e.m. Statistical significance was determined by a two-tailed, unpaired Student’s t-test. The experiments were repeated three times. The source data can be found in Supplementary Table 4.