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. 2013 Sep 18;1838(4):1058–1067. doi: 10.1016/j.bbamem.2013.09.004

Table 1.

List of identified viroporin proteins.a

Name of virus Name of viroporin # of amino acid Oligomeric state Ion or substrate References
IAV M2 97 Tetramer H+ Ref. [37], [38], [74]
IBV BM2 115 Tetramer H+ Ref. [39]
HCV p7 63 Hexamer Cation Ref. [18], [62]
HIV-1 Vpu 81 Pentamer Cation Ref. [70], [71], [90]
SARS-CoV 3a 274 Tetramer K+ Ref. [72]
E 76 Pentamer Na+, K+ Ref. [91]
Alphavirus 6 K 61 N/A b Na+, K+, Ca2 + Ref. [8]
Poliovirus VP4 68 N/A b RNA Ref. [23]
2B 97 N/A b Ca2 + Ref. [7], [92]
HPV E5 83 N/A b N/A Ref. [93], [94]
PBCV-1 Kcv 94 Tetramer K+ Ref. [21], [95]
a

The viruses listed are influenza A virus (IAV), influenza B virus (IBV), hepatitis C virus (HCV), human immunodeficiency virus type 1 (HIV-1), severe acute respiratory syndromes-associated coronavirus (SARS-CoV), alphavirus, poliovirus, human papillomavirus (HPV), and Paramecium bursaria chlorella virus 1 (PBCV-1).

b

Pore formation indicated but a defined oligomeric state either does not exist or is not characterized.