Table 2.

Histological indices describing cerebellar development in neonatal rabbits treated with/without systemic glycerol.

	Dose of glycerol (g/kg)
	0	3.25	6.5
Number	4	4	3
Lobes I–III perimeter (mm)	29.1 ± 2.7	24.2 ± 1.6	19.8 ± 1.1*
Primary fissure length (µm)	1345 ± 71	1031 ± 46†	810 ± 35‡
Internal granular layer thickness (µm)	69.5 ± 2.0	64 ± 5.6	74.1 ± 2.6
Molecular layer thickness (µm)	171 ± 4	143 ± 9	166 ± 8
External granular layer thickness (µm)	35.5 ± 4.4	18.9 ± 2.8‡	26.2 ± 3.1*
Purkinje cell density (% total area)	0.287 ± 0.003	0.285 ± 0.013	0.319 ± 0.008*
Ki-67 immunolabeling (% total area)	0.627 ± 0.122	0.452 ± 0.121	0.125 ± 0.060*

Data are presented as means ± SEM. Kruskal-Wallis test with Dunn's multiple comparison test were performed on the Purkinje density and Ki-67 positivity. ANOVA with Dunnett's post hoc comparisons to control (0) was used for the rest:

^{*, †, ‡}P ≤ 0.05, 0.01, or 0.001 respectively.