Table 3.
Published network-based methods for GWAS data analysis
| Method | Genetic measurement | Strategy | Association test | Randomization test | Software | Reference |
|---|---|---|---|---|---|---|
| jActiveModule | Quantitative | Combinatory | No | Yes | Stand-alone | (Baranzini et al. 2009; Burcu and Osman Ugur 2011; Liu et al. 2011) |
| dmGWAS | Quantitative | Combinatory | Yes | Yes | Stand-alone | (Jia et al. 2011b) |
| NIMMI | Quantitative | Combinatory | No | No | Stand-alone | (Akula et al. 2011) |
| DAPPLE | Binary | Prioritization | No | Yes | Online | (Rossin et al. 2011) |
| Lee et al. | Quantitative | Prioritization | No | NA | NA | (Lee et al. 2011) |
| NetworkMiner | Quantitative | Combinatory | No | Yes | Online | (Garcia-Alonso et al. 2012) |