Table 4.
Network-assisted GWAS studies
| Phenotype/disease | Method | Type | Epub. date | Reference |
|---|---|---|---|---|
| Multiple sclerosis | jActiveModule | Methodology | Mar. 2009 | (Baranzini et al. 2009) |
| Multiple sclerosis | jActiveModule | Application | May 2010 | (Baranzini et al. 2010) |
| Breast cancer and pancreatic cancer | dmGWAS | Methodology | Nov. 2010 | (Jia et al. 2011b) |
| Obstructive sleep apnea | jActiveModule | Application | Dec. 2010 | (Liu et al. 2011) |
| Rheumatoid arthritis, Crohn’s disease, height, lipids, and type 2 diabetes | DAPPLE | Methodology | Jan. 2011 | (Rossin et al. 2011) |
| Crohn’s disease and type 2 diabetes | Label propagation algorithm | Methodology | May 2011 | (Lee et al. 2011) |
| Seven immune-mediated and autoimmune diseases | DAPPLE | Application | Aug. 2011 | (Cotsapas et al. 2011) |
| Mood disorders | Michigan Molecular Interactions (MiMI) | Application | 2011 | (Detera-Wadleigh and Akula 2011) |
| Height, Crohn’s disease | NIMMI | Methodology | Sep. 2011 | (Akula et al. 2011) |
| Rheumatoid arthritis | PANOGA | Application | Oct. 2011 | (Burcu and Osman Ugur 2011, 2012) |
| Bipolar disorder | Greedy search modified from jActiveModule | Methodology | Apr. 2012 | (Pedroso et al. 2012) |
| Bipolar disorder | NetworkMiner | Methodology | Jun. 2012 | (Garcia-Alonso et al. 2012) |
| Schizophrenia | dmGWAS | Application | Jul. 2012 | (Jia et al. 2012c) |
| Alzheimer disease | DAPPLE | Application | Apr. 2012 | (Raj et al. 2012) |
| Multiple sclerosis | DAPPLE | Application | Oct. 2012 | (Ragnedda et al. 2012) |
| Pediatric stroke | dmGWAS | Application | Dec. 2012 | (Arning et al. 2012) |