Table 1.

Covalently Bound ω-OH Cer Content Declines in EFAD Mouse Epidermis

	CLE-ωOH Cer* (μg/mg dry epidermis)	CLE Content** (% of normal mouse)
Normal	1.88 + 0.12	100.0 + 13.0
EFAD	0.82 + 0.07***	49.7 + 10.5***

Legend:

^*Covalently bound lipids were isolated, and the resultant Cer fractions were quantitated by HPTLC-scanning densitometry, as described in [1].

^**Using randomly-obtained electron micrographs (n=10), CLE content was determined as the percent of the overall inter-desmosomal corneocyte-surface covered by CLE, as described by Behne, et al. [30].

^***P < 0.01 vs. normal control mice.