Skip to main content
. 2014 Mar 5;9(3):e89841. doi: 10.1371/journal.pone.0089841

Figure 6. Western blot analysis showing the upregulation of pro-caspase-3 expression by doxycycline in SKOV3/DDP cells but not in SKOV3 cells.

Figure 6

Comparison of Akt, ERK, CXCR4 and pro-caspase-3 expression in two cell lines. There was no significant difference of Akt (A) phosphorylation in the two cell lines. ERK phosphorylation (B), CXCR4 (C) and pro-caspase-3 (D) expression in SKOV3/DDP cells were all lower than those in SKOV3 cells, respectively. Pro-caspase-3 expression was increased significantly by doxycycline treatment in SKOV3/DDP cells, while did not change in SKOV3 cells (E). n = 3. *, p<0.05, **, p<0.01.