. 2014 Mar 5;9(3):e90296. doi: 10.1371/journal.pone.0090296

Table 2. Percentage of Allium cells with various chromosomal aberrations after exposure for 48 hr to ZDV or NVP.

Chemical Exposure (μM)	Cells evaluated (n)	Sticky chromosomes^a (%)	Chromatin bridges^b (%)	Vagrant forms^c (%)	Binucleate (%)^d	Multipolar mitosis^e (%)	Chromosomal Fragments^f (%)	Total Aberration (%)
None	1000	0	0	0	0	0	0	0
6.5 ZDV	736	25.0	12.5	6.3	4.2	-	6.3	56.3
16.3 ZDV	744	23.3	7.0	16.3	2.3	2.3	-	55.8
32.5 ZDV	747	24.6	8.8	12.3	3.5	1.8	3.5	56.1
65.0 ZDV	690	57.9	-	-	5.3	-	-	63.2
9.3 NVP	503	36.0	-	20.0	-	-	-	56.0
23.1 NVP	361	53.3	-	6.7	-	-	-	60.0
46.3 NVP	429	61.9	-	-	4.8	-	-	66.7
92.5 NVP	720	56.8	-	2.7	5.4	-	-	64.9

Sticky chromosomes refer to the tendency of chromosome arms or entire chromosomes to stick together.

Chromatin bridges occur in mitosis when the telomeres of sister chromatids fuse together and fail to completely segregate into their respective daughter cells. ^c Vagrant forms refer to chromosomal formations different from the normal formation during mitosis.

Binucleated cells have more than one nucleus. ^e Multipolar mitosis occurs when the chromosomal material is pulled to more than two poles, resulting in the formation of a corresponding number of nuclei. ^f Chromosomal fragments refer to fragments of a chromosome that may be lacking a centromere and so is often lost when the cell divide.