Table 3.
Latency analysis of statistically significant community-acquired infections.
| INFECTION | 13–30 Months OR (95% CI)2 | 31–48 Months OR (95% CI)2 | 49–72 Months OR (95% CI)2 | >72 Months OR (95% CI)2 | p-value for trend |
|---|---|---|---|---|---|
| AML 1991–2005 | |||||
| Bronchitis | 1.06 (0.97, 1.16) | 1.43 (1.31, 1.57) | 1.24 (1.14, 1.35) | 1.14 (1.04, 1.24) | 0.732 |
| Influenza | 1.23 (1.11, 1.37) | 1.15 (0.95, 1.40) | 1.12 (0.94, 1.33) | 1.04 (0.87, 1.24) | 0.090 |
| Pharyngitis | 1.02 (0.90, 1.17) | 1.27 (1.11, 1.45) | 1.19 (1.05, 1.34) | 1.09 (0.97, 1.23) | 0.611 |
| Pneumonia | 1.30 (1.18, 1.43) | 1.39 (1.25, 1.54) | 1.26 (1.13, 1.40) | 1.19 (1.07, 1.33) | 0.153 |
| Sinusitis | 1.21 (1.10, 1.34) | 1.32 (1.19, 1.47) | 1.23 (1.12, 1.35) | 1.18 (1.08, 1.30) | 0.566 |
| Cystitis1 | 1.04 (0.95, 1.13) | 1.15 (1.06, 1.26) | 1.14 (1.05, 1.24) | 1.17 (1.08, 1.27) | 0.033 |
| MDS 2001–2005 | |||||
| Bronchitis | 1.22 (1.05, 1.41) | 1.50 (1.30, 1.73) | 1.32 (1.17, 1.49) | 1.08 (0.95, 1.22) | 0.002 |
| Influenza | 1.45 (1.27, 1.65) | 1.31 (0.96, 1.79) | 1.14 (0.88, 1.47) | 1.01 (0.79, 1.29) | 0.004 |
| Pharyngitis | 1.21 (0.99, 1.50) | 1.63 (1.35, 1.98) | 1.32 (1.11, 1.57) | 0.96 (0.80, 1.14) | 0.006 |
| Pneumonia | 1.44 (1.24, 1.67) | 1.77 (1.52, 2.07) | 1.72 (1.50, 1.97) | 1.22 (1.05, 1.43) | 0.130 |
| Sinusitis | 1.10 (0.92, 1.31) | 1.56 (1.33, 1.82) | 1.38 (1.21, 1.57) | 1.08 (0.94, 1.23) | 0.226 |
| Cystitis1 | 1.22 (1.06, 1.40) | 1.22 (1.06, 1.40) | 1.42 (1.26, 1.59) | 1.18 (1.05, 1.32) | 0.885 |
| Cellulitis | 1.64 (1.43, 1.88) | 1.52 (1.31, 1.76) | 1.64 (1.44, 1.87) | 1.26 (1.09, 1.45) | 0.016 |
| Herpes zoster | 1.45 (1.13, 1.86) | 1.46 (1.12, 1.92) | 1.24 (0.95, 1.63) | 1.11 (0.84, 1.46) | 0.101 |
| Gastroenteritis | 1.50 (1.08, 2.06) | 1.76 (1.26, 2.46) | 1.36 (0.97, 1.89) | 1.04 (0.73, 1.49) | 0.080 |
| CML 1991–2005 | |||||
| Bronchitis | 1.06 (0.92, 1.22) | 1.43 (1.24, 1.64) | 1.34 (1.18, 1.51) | 1.08 (0.95, 1.24) | 0.942 |
| Pneumonia | 1.41 (1.23, 1.61) | 1.83 (1.58, 2.11) | 1.49 (1.29, 1.73) | 1.28 (1.09, 1.51) | 0.230 |
| Sinusitis | 1.01 (0.86, 1.19) | 1.29 (1.10, 1.52) | 1.24 (1.07, 1.43) | 1.22 (1.06, 1.41) | 0.122 |
| Cellulitis | 1.49 (1.31, 1.70) | 1.47 (1.27, 1.70) | 1.38 (1.20, 1.60) | 1.36 (1.17, 1.59) | 0.281 |
| MPN 2001–2005 | |||||
| Cellulitis | 1.32 (1.10, 1.59) | 1.39 (1.15, 1.67) | 1.54 (1.30, 1.83) | 1.11 (0.91, 1.36) | 0.369 |
Abbreviations: AML= Acute myeloid leukaemia, MDS = Myelodysplastic Syndrome, CML= Chronic myeloid leukaemia, MPN = Myeloproliferative neoplasms, OR = Odds Ratio, CI = Confidence Intervals
1
Females only.
2
Odds ratios (OR) and 95% confidence intervals (CI) were adjusted for age (66–69, 70–74, 75–79, 80–84 and 85+ years), gender and year of diagnosis selection.
p-value to 3 decimal places.