The effect of GPx1, GPx2 and Nox1 gene on the length of small and large intestine in 50-day-old mice. Panel A. The length of small intestine in male mice. The number of mice in each group is 9 DKO, 9 TKO, 8 GPx1+/−GPx2−/−Nox1+, 11 GPx1+/− GPx2−/−Nox1−, 5 GPx1−/−GPx2+/−Nox1+, 3 GPx1−/−GPx2+/−Nox1−, 2 WT Nox+ and 2 WT Nox-. Panel B. The length of colon in male mice. The number of mice in each group is 22 DKO, 12 TKO, 9 GPx1+/−GPx2−/−Nox1+, 21 GPx1+/−GPx2−/−Nox1−, 6 GPx1−/− GPx2+/−Nox1+, 5 GPx1−/−GPx2+/−Nox1−, 12 WT Nox+ and 26 WT Nox-. The group marked with a* and b* are different (a*>b*, t-test). However, there is no difference when analyzed with a multiple comparison test. Panel C. The length of small intestine in female mice. The number of mice in each group is 13 DKO, 22 het-DKO, 6 TKO and 5 non-DKO. Panel D. The length of colon in female mice. The number of mice in each group is 20 DKO, 25 het-DKO, 6 TKO and 6 non-DKO. The group with significant different length is marked with a different letter, where a>b. The error bars show one SD.