WT and 5-LO−/− macrophages were transfected with 30 nM of the mimics miR-155, miR-146b, or miR-125b for 48 h, stimulated with LPS for 24 h, and TNF-α (A) and NO (B) levels were detected by ELISA and Griess reaction, respectively. Data represent mean ± SEM from 3 individual experiments, each performed in triplicate. *P < 0.05 versus unstimulated WT; #P < 0.05 versus stimulated WT.