Table 1.
Characteristics of RA and Non-RA Cohorts.
| Characteristic | RA (n=813) | Non-RA (n=813) | p |
|---|---|---|---|
| At incidence/index | |||
| Ageˆ (y) | 55.9 ± 15.7 | 55.9 ± 15.7 | 0.9 |
| Female sex | 556 (68%) | 556 (68%) | 0.9 |
| White race | 761 (94%) | 771(96%) | 0.1 |
| BMI (kg/m2) | 27.8 ± 6.0 | 27.7 ± 6.0 | 0.8 |
| Smoking status | 0.002 | ||
| Never | 364 (45%) | 435 (54%) | |
| Current | 178 (22%) | 144 (18%) | |
| Former | 271 (33%) | 234 (29%) | |
| Diabetes Mellitus | 79 (10%) | 67 (8%) | 0.3 |
| Hypertension | 307 (38%) | 275 (34%) | 0.1 |
| CVD | 87 (11%) | 89 (11%) | 0.9 |
| Heart failure | 23 (3%) | 23 (3%) | 0.9 |
| eGFR | 0.008 | ||
| Mean (mL/min/1.73 m2) | 85.7 ± 19.7 | 83.1 ± 19.8 | |
| Median (mL/min/1.73 m2) | 87.1 [73.4-98.9] | 83.5 [70.8-96.8] | |
| Presence of eGFR <60* | 74 (9%) | 74 (9%) | 0.9 |
| Presence of eGFR <45** | 19 (2%) | 22 (3%) | 0.8 |
| Length of follow-up (y) | 9.6 ± 6.9 | 10.9 ± 7.2 | -- |
Note: Values for categorical variables are given as number (percentage); values for continuous variables are given as mean ± standard deviation or median [interquartile range].
CVD: Cardiovascular disease; eGFR: estimated glomerular filtration rate; CKD: chronic kidney disease; BMI, body mass index; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; RA, rheumatoid arthritis
*
eGFR <60 was defined as two consecutive eGFRs <60 mL/min/1.73 m2 at least 90 days apart using the CKD-EPI creatinine equation.
**
eGFR <45 was defined as two consecutive eGFRs <45 mL/min/1.73 m2 at least 90 days apart using the CKD-EPI creatinine equation.