Table 4.
Risk factors for past three month marijuana use for youth participating in the PHACS AMP protocol, 2007–2011; adjusted odd ratios for full sample and by HIV status
| Full sample | PHIV + | PHEU | |||||
|---|---|---|---|---|---|---|---|
|
| |||||||
| Risk Factor | aORa (95% CI) | P-value | aORa (95% CI) | P-value | aORa (95% CI) | P-value | Interaction P-value |
| Alcohol use in home | 1.21 (0.76, 1.95) | 0.42 | 1.02 (0.59, 1.75) | 0.96 | 1.98 (0.75, 5.23) | 0.17 | 0.24 |
| Cigarette use in home | 0.89 (0.49, 1.61) | 0.70 | 0.77 (0.38, 1.55) | 0.46 | 1.35 (0.46, 3.96) | 0.59 | 0.39 |
| Any substance use in home | 1.06 (0.51, 2.22) | 0.88 | 0.93 (0.39, 2.22) | 0.87 | 1.63 (0.48, 5.48) | 0.43 | 0.46 |
| Marijuana use in home | 10.3 (4.76, 22.27) | <0.001 | 11.42 (3.52, 37.09) | <0.001 | 9.19 (3.39, 24.91) | <0.001 | 0.78 |
| Caregiver physical health | 1.19 (0.55, 2.59) | 0.66 | 1.13 (0.44, 2.91) | 0.80 | 1.33 (0.34, 5.27) | 0.68 | 0.85 |
| Caregiver psychiatric diagnosis | 1.22 (0.60, 2.48) | 0.59 | 0.92 (0.35, 2.41) | 0.86 | 1.97 (0.70, 5.57) | 0.20 | 0.29 |
| Behavioral symptoms index (BASC) | 1.03 (1.01, 1.06) | 0.011 | 1.03 (1.00, 1.06) | 0.027 | 1.03 (0.98, 1.08) | 0.21 | 0.89 |
| Conduct problems subscale (BASC) | 1.06 (1.03, 1.08) | <0.001 | 1.06 (1.03, 1.10) | <0.001 | 1.04 (1.00, 1.08) | 0.038 | 0.44 |
| Emotional symptom index (BASC) | 1.02 (0.99, 1.05) | 0.27 | 1.03 (0.99, 1.07) | 0.10 | 0.97 (0.88, 1.06) | 0.48 | 0.21 |
| Stressful life events: at least one bad event | 1.80 (0.66, 4.95) | 0.25 | 2.17 (0.71, 6.64) | 0.18 | 1.04 (0.16, 6.81) | 0.97 | 0.16 |
| Stressful life events: total bad events | 1.14 (0.96, 1.35) | 0.12 | 1.27 (1.02, 1.58) | 0.036 | 0.96 (0.79, 1.18) | 0.73 | 0.06 |
| WIAT math score | 1.01 (0.98, 1.04) | 0.49 | 1.01 (0.98, 1.04) | 0.63 | 1.02 (0.97, 1.07) | 0.41 | 0.61 |
| WIAT word score | 1.02 (1.00, 1.05) | 0.07 | 1.02 (0.99, 1.05) | 0.12 | 1.02 (0.97, 1.06) | 0.48 | 0.78 |
| Parent-child communication < 40 | 1.05 (0.50, 2.20) | 0.89 | 1.06 (0.46, 2.44) | 0.90 | 1.05 (0.28, 3.91) | 0.95 | 0.99 |
| Parent-child involvement < 40 | 0.74 (0.37, 1.49) | 0.40 | 0.53 (0.23, 1.20) | 0.13 | 1.37 (0.41, 4.57) | 0.61 | 0.19 |
| Parent-child relationship autonomy < 40 | 1.42 (0.72, 2.80) | 0.31 | 0.91 (0.37, 2.25) | 0.83 | 2.91 (0.97, 8.71) | 0.05 | 0.11 |
| Parent-child relationship limit setting < 40 | 1.31 (0.35, 4.91) | 0.69 | 0.84 (0.10, 7.27) | 0.87 | 1.85 (0.31, 11.12) | 0.50 | 0.58 |
| Parent-child relationship support < 40 | 0.48 (0.13, 1.76) | 0.27 | 0.27 (0.03, 2.68) | 0.26 | 0.85 (0.17, 4.30) | 0.84 | 0.42 |
| Parent-child relationship satisfaction < 40 | 1.16 (0.39, 3.40) | 0.79 | 1.06 (0.25, 4.46) | 0.94 | 1.35 (0.31, 5.90) | 0.69 | 0.81 |
| Parent-child relationship composite score | 0.75 (0.39, 1.44) | 0.38 | 0.59 (0.27, 1.29) | 0.19 | 1.24 (0.40, 3.88) | 0.71 | 0.28 |
| HIV status | 0.73 (0.37, 1.46) | 0.37 | |||||
|
|
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| PHIV+ Only | |||||||
|
| |||||||
| CD4 >500 cell/mm3 | 1.56 (0.85, 2.83) | 0.15 | |||||
| HIV RNA >400 copies/mL | 1.17 (0.66, 2.05) | 0.59 | |||||
| Ever had a CDC Class C diagnosis | 0.69 (0.18, 2.67) | 0.59 | |||||
| Missed ART dose in last 7 days | 1.65 (0.92, 2.97) | 0.09 | |||||
| Knows HIV status | 0.96 (0.49, 1.78) | 0.84 | |||||
|
| |||||||
PHACS Pediatric HIV/AIDS Cohort Study, AMP Adolescent Master Protocol, PHIV+ perinatally HIV-infected, PHEU perinatally HIV-exposed but uninfected, aOR adjusted odds ratio, CI confidence interval, BASC Behavioral Assessment System for Children, WIAT Wechsler Individual Achievement Test, ART antiretroviral therapy
Adjusted for caregiver education, household income, caregiver type, age, race, ethnicity, and sex. Models not stratified by HIV status or not pertaining to PHIV+ subjects include statistical control for HIV status. With the exception of models used to estimate the effects of alcohol, cigarette, marijuana, or any substance use in the home, the models include an additional adjustment for caregiver substance use.