Table 2.
Secondary end points. Values represent the previous 24 h from time queried, unless otherwise indicated.
| Perineural Infusion: | Ropivacaine (n=30) | Placebo (n=30) | P-value |
|---|---|---|---|
| Pain (NRS POD 1 00:00–12:00)§ | 3.6 (2.0–4.0) | 3.7 (2.5–4.6) | 0.183 |
| Morphine equivalents (mg)§ | |||
| Intraoperative§ | 3.0 (2.5–4.5) | 2.5 (2.5–5.0) | 0.752 |
| Recovery room§ | 1.0 (0.0–2.8) | 2.4 (1.0–5.5) | 0.013 |
| POD 1 (00:00–12:00)§ | 1.5 (0.0–8.5) | 3.3 (1.4–10.3) | 0.402 |
| Oral opioid (oxycodone, mg) | |||
| POD 4 | 10 (0–23) | 10 (0–20) | 0.376 |
| POD 8 | 1 (0–14) | 0 (0–8) | 0.840 |
| Nausea (0–10, 10=vomiting) | |||
| POD 1§ | 0 (0-0) | 0 (0–6) | 0.053 |
| POD 4 | 0 (0-0) | 0 (0-0) | 0.277 |
| POD 8 | 0 (0-0) | 0 (0-0) | 0.294 |
| Difficulty sleeping (# subjects) | |||
| POD 1§ | 9 | 16 | 0.116 |
| POD 4 | 8 | 8 | 1.000 |
| POD 8 | 10 | 8 | 0.848 |
| POD 28 | 6 | 6 | >0.999 |
| Awakenings due to pain (#/subject) | |||
| POD 1§ | 0 (0–1) | 1 (0–3) | 0.306 |
| POD 4 | 0 (0–1) | 0 (0–1) | 0.828 |
| POD 8 | 0 (0–2) | 0 (0-0) | 0.127 |
| POD 28 | 0 (0-0) | 0 (0-0) | 0.445 |
Values are reported as median (interquartile) or number of subjects, as indicated
§
During perineural infusion
NRS: Numeric Rating Scale
POD: postoperative day
Oral opioid and nausea queried exclusively on POD 4/8 and 1/4/8, respectively