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. Author manuscript; available in PMC: 2015 Feb 21.
Published in final edited form as: ACS Chem Biol. 2013 Nov 25;9(2):433–442. doi: 10.1021/cb4006886

Figure 3.

Figure 3

Hit Validation. a) Structures of the most efficacious 5 hits from the LOPAC screen. Concentration response curves (CRC) for the same compounds with b) VopS and c) PAD4. The CRC for PAD4 were generated using the PAD4 targeted FP-ABPP assay.