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Mechanism of inhibition values for VopS
| Compound | Varied substrate | Mechanism of inhibition |
Kis (µM) |
Kii (µM) |
|---|---|---|---|---|
| 1 | Cdc42 | Non-competitive | 20 ± 1 | |
| ATP | Non-competitive | 41 ± 5 | ||
| 3 | Cdc42 | Non-competitive | 99 ± 16 | |
| ATP | Non-competitive | 50 ± 6 | ||
| 4 | Cdc42 | Competitive | 6 ± 1 | |
| ATP | Non-competitive | 26 ± 4 | ||
| 5 | Cdc42 | Competitive | 410 ± 110 | |
| ATP | Mixed | 66 ± 19 | 310 ± 38 |
